Guillaume C. Macneil

Email: guillaume@gcmacneil.com

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Hi! I'm a research assistant in the Gruszka Lab at the University of Oxford. I use computational approaches to investigate chromatin replication and better understand (epi)genetic inheritance. More generally, I am interested in single-molecule biophysics and the computational modelling of biological systems.

When I'm not in the lab, you can find me on the mats doing judo, running all over the place, or camping and hiking with friends. If you're after a better chess player or a faster runner, try my brother Elliott Macneil.

Projects:

Education:

Incoming PhD Student, Condensed Matter Physics, University of Oxford, Oct 2026 - Mar 2030

I am an incoming PhD student at the Gruszka Lab. I will be researching the mechanics of chromatin replication and its impact on genetic and epigenetic inheritance.

MEng, Computer Science, University of Durham, Oct 2021 - Jun 2025

First class degree with honours. Master's Project: The Multi-weight s-Circuit Problem: an Application to Route Generation; supervised by Prof. Iain Stewart.

Experience and Employment:

Research Assistant in the Gruszka Lab, Kavli Institute for Nanoscience Discovery, University of Oxford, Sep 2025 - Sep 2026 (Present)

I develop computational pipelines for analysing real-time chromatin replication using single-molecule TIRF.

Ciliated Tissue Modelling in the Boselli Lab, Biophysical Sciences Institute, University of Durham, Jun 2024 - Aug 2024

Supervised by Dr. Francesco Boselli, I made CiliaSim for modelling aperiodic ciliated tissues. Supported by the Royal Microscopical Society and BSI summer studentships.

Computer Science Demonstrator, Department of Computer Science, University of Durham, Oct 2023 - May 2025

I taught Data Science (probability, data cleaning and analytics, image processing and computer graphics) and Programming (git version control and web development).

Personal Interests:

Competitive Judoka - 2024/2025 Durham University Judo Club Men's Captain - BUCS 2024/2025 2nd place - Invited to the European University Games 2025.

Long Distance Hiker - Cambrian Way 2022 - GR20 2024 - Hadrian's Wall 2025 - West Highland Way 2025/26.